Semester Two Final Examinations, 2018 STAT1201 Analysis of Scientific Data THE UNIVERSITY OF QUEENSLAND AUSTRALIA AC This exam paper must not be removed from the venue Venue Seat Number Student Number Family Name First Name School of Mathematics & Physics EXAMINATION Semester Two Final Examinations, 2018 STAT1201 Analysis of Scientific Data This paper is for St Lucia Campus, Gatton Campus (External) and Gatton Campus students. Examination Duration: 120 minutes Reading Time: 10 minutes For Examiner Use Only Exam Conditions: Question Mark This is a Central Examination 1 This is a Closed Book Examination - specified materials permitted 2 During reading time - Write only on rough paper provided This examination paper will be released to the Library 3 Materials Permitted In The Exam Venue: 4 (No electronic aids are permitted e.g. laptops, phones) Calculators - Casio FX82 series or UQ approved (labelled) An annotated copy of A Portable Introduction to Data Analysis (any edition) is also permitted. Total Materials To Be Supplied To Students: None Instructions To Students: There are 50 marks available on this exam from 4 questions. Write your answers in the spaces provided in pages 2-14 of this examination paper. Show your working and state conclusions where appropriate. Pages 15-19 give formulas and statistical tables. Those pages will not be marked. The textbook can have any amount of annotation on its pages. Loose sheets of paper or post-it notes are not permitted. Page tabs are allowed. Page 1 of 19
Semester Two Final Examinations, 2018 STAT1201 Analysis of Scientific Data Question 1 13 marks A recent study aimed to evaluate the clinical effects of the drug rivastigmine on the symptoms of schizophrenia when used alongside standard antipsychotic medication. A total of 36 patients with a diagnosis of schizophrenia entered into a 12-week, double- blind, clinical trial with random assignment to rivastigmine or placebo. Scores on the Mini Mental State Examination (MMSE) before and after the trial were used as the primary outcome measure. (a) The baseline MMSE score for the 18 patients in the rivastigmine group had a mean of 24.1 and a standard deviation of 2.9 while the 18 patients in the placebo group had a mean MMSE score of 23.0 and a standard deviation of 3.2. Does this give any evidence of a difference in the baseline MMSE scores between the two groups? State the null and alternative hypotheses, and use an appropriate test statistic to determine the P-value. What do you conclude? [5 marks] (b) Interpret your conclusion from (a) in the context of the random assignment to groups. [1 mark] Page 2 of 19
Semester Two Final Examinations, 2018 STAT1201 Analysis of Scientific Data (c) After the 12-week trial, the 18 subjects in the rivastigmine group had an improved mean MMSE score of 27.1. The mean of the 18 changes in MMSE score was 3.0 with standard deviation 3.7. Does this give any evidence that mean MMSE score increases for patients with rivastigmine? State the null and alternative hypotheses, and use an appropriate