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Stem Cells and Asymmetric Cell Division

Stem Cells and Differentiation Lecture 2 BIOM2208 Joe Rothnagel Content Asymmetry of cell division Regulation by intrinsic & extrinsic factors Daughter cells/ TA cells identification Extrinsic and intrinsic factors required for stem cell maintenance Culture of stem cells induced pluripotent stem cells Asymmetric cell division Stem cells are self-renewing. That is after each cell division, one daughter cell retains all the characteristics of the parental cell. STEM CELL STEM CELL (e.g., hematopoletic stem cell) SPECIALIZED CELL (e.g., neuron)