School of Life and Health Sciences Department of Biosciences BY3BC1 - Medical Biochemistry Open-book Paper ANSWER ONE QUESTION. 1. Identify and briefly describe clinical conditions where cardio vascular function is compromised and discuss how both biochemical and non-biochemical tests can lead to an appropriate diagnosis. 2. Critically discuss the principles of using serum enzymes and other proteins as biomarkers of disease. Appraise the importance of reference ranges, how they are derived and describe using examples, the characteristics of an ideal biomarker. 3. Describe conditions of malabsorption affecting the gastrointestinal tract (50% of the marks) and discuss using examples, the analytic tests used to diagnose these disorders (50% of the marks). END OF EXAMINATION PAPER