BIO00009C Examination Candidate Number: Desk Number: University of York Department of Biology B. Sc Stage 1 Degree Examinations 2016-17 Genetics and Evolution Time allowed: 1 hour and 30 minutes Total marks available for this paper: 50 · Answer all questions in the spaces provided on the examination paper . The marks available for each question are indicated on the paper · A calculator will be provided For marker use only: 1 2 3 4 5 6 7 8 9 10 11 12 For office use only: Total as % page 1 of 9
BIO00009C Answer all questions in the spaces provided 1. Describe the experiment that identified the human cdc2 gene. (4 marks) 2. Wild-type Antirrhinum plants have red flowers. Seven white flowered mutants were identified by mutagenesis. The mutants were crossed to each other and wild-type (WT). The flower colour of the progeny was recorded and presented in the table below. mutant a mutant b mutant c mutant d mutant e mutant f mutant g WT red red red red red red rec mutant a white red white red white red red mutant b white red red red white white mutant c white red white red red mutant d white red red red mutant e white red red mutant f white white mutant g white a) Why were all the mutant lines crossed to the wild type line? (1 mark) page 2 of 9
BIO00009C b) Write down the complementation groups you have identified. (3 marks) c) How many genes have been identified with roles in the production of red flowers? (1 mark) 3. Mimulus cardinalis produces red flowers. Mutagenesis screens have identified recessive mutations that generate yellow and orange flowers. A yellow flowered mutant line was crossed to an orange flowered mutant line. Flower colour in the F2 generation segregated in a ratio of 9 red: 4 yellow and 3 orange flowers. Draw a simple diagram of the biosynthetic pathway that generates the red flower colour that is consistent with this ratio. (3 marks) Turn over page 3 of 9