. PAPER REFERENCE: 0230741 EXAMINATION NUMBER: DESK NUMBER: UNIVERSITY OF YORK DEPARTMENT OF BIOLOGY B. Sc. Degree Examinations 2010-2011 Module no: 0230741 Module title: CANCER AND THE CELL CYCLE TIME ALLOWED: 1 HOUR AND 30 MINUTES (1.5 HOURS) This paper has two parts: Part i Short answer questions (30 minutes) This part counts for 40% of your mark for the module. · Answer ALL questions. · Write your answers in the spaces provided on the examination paper. · The marks available are indicated on the paper. Part ii Essay question (60 minutes) This part counts for 60% of your mark for the module. · Answer ONE question in the answer book provided. . Indicate the question number answered on the front of the answer book. . Write your examination candidate number on the front of each booklet used. . At the end of the examination, attach all the booklets together. For office use only: 1 2 3 4 5 SA Total Essay (100) Final mark if paper moderated: Page 1 of 7 Essay *0.6 Total -- - turn over -
. MODULE 0230741 CANCER AND THE CELL CYCLE Part i: Short answer questions Answer all questions in the spaces provided. 1. Briefly describe an in vivo experimental approach to determine the molecular mechanisms involved in the metastasis of breast cancer cells. (8 marks) The space above this line should be sufficient for your answer Page 2 of 7 - turn over -
. MODULE 0230741 CANCER AND THE CELL CYCLE 2. a) In what cell type do most adult cancers arise? (1 mark) b) What is the main cause of sporadic cancers? (1 mark) c) Give two reasons why different people develop different types of cancer. (2 marks) i) ii) d) Why is bladder cancer the most costly cancer to manage? (2 marks) The space above this line should be sufficient for your answer Page 3 of 7 - turn over -