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Pharmacology

ACTIVE LEARNING TEMPLATE: Medication MEDICATION Digoxin/ Lanoxicaps/ Lanoxin CATEGORY CLASsDigitalis glycosides REVIEW MODULE CHAPTER PURPOSE OF MEDICATION Expected Pharmacological Action Therapeutic Use Increases force and velocity of myocardial contraction, resulting in + inotropic effects Decreases conduction rate and increases effective refactory period of AV node For Tx of mild to moderate heart failure with rapid digitization Complications Medication Administration -Arythmias -Heart block -Electrolyte imbalances -Anorexia Nausea and vommiting -Diarrhea -confusion -dizziness -drowsiness -restlessness -amnesia -weight gain -visual disturbances (seeing green, yellow, or halos) May be given PO or IV Most common via IV and administered slowly over 5 min 10-15 mcg per kg of body weight Contraindications/Precautions Hx/presence of digitalis toxicity/idiosyncratic reaction to sigoxin, V-fib, v-tach (unless HF occurs unrelated to digoxin therapy) Nursing Interventions Monitor apicle pulsefor 1 min before administering Hold dose if pulse < 60 in adult Interactions Must be weaned off Arbutimine, quinidine, amphotericin B, macrolide antibiotics, prpafenone, cyclosorine, verapamil, hydroxychloroquine, trimethoprim, ketoconazole, amiodarone Client Education Take as prescribed; possible toxicity from taking too much, decreased effectiveness if taking too little. Take pulse before taking med, notify HCP if pulse is below 60bpm. Notify HCP if GI distress occurs. Evaluation of Medication Effectiveness Normal cardiac rythym, proper functioning of the heart muscles, adequate tissue perfusion/oxygenation Do not double up on doses if previous dose was missed-> ACTIVE LEARNING TEMPLATES THERAPEUTIC PROCEDURE A7