3. Fill up the blanks in the following sentence by selecting...

3. Fill up the blanks in the following sentence by selecting the correct option. The thin filaments of myofibril contain (A) actin and two filaments of $\underline{(B)}$ protein along with $\underline{\text { CC }}$ protein for masking binding site for myosin. A $\quad$ B $C$ (a) $1 \mathrm{~F}$ troponin tropomyosin (b) IF tropomyosin troponin (c) $2 \mathrm{~F}$ troponin tropomyosin (d) $2 \mathrm{~F}$ tropomyosin troponin

3. Fill up the blanks in the following sentence by selecting the correct option. The thin filaments of myofibril contain (A) actin and two filaments of $\underline{(B)}$ protein along with $\underline{\text { CC }}$ protein for masking binding site for myosin. A $\quad$ B $C$
(a) $1 \mathrm{~F}$ troponin tropomyosin
(b) IF tropomyosin troponin
(c) $2 \mathrm{~F}$ troponin tropomyosin
(d) $2 \mathrm{~F}$ tropomyosin troponin

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Key Concepts

Troponin

Troponin is a protein complex associated with the thin filaments that includes three subunits. It is responsible for sensing changes in intracellular calcium levels, which in turn triggers a conformational change in tropomyosin to expose the myosin binding sites on actin and facilitate muscle contraction.

Thin Filaments

Thin filaments are essential components of myofibrils in muscle cells. They are composed of actin along with associated regulatory proteins and play a critical role in muscle contraction by serving as the tracks along which the motor protein myosin moves.

Actin

Actin is a globular protein that polymerizes to form long filaments in muscle cells. It provides the structural framework of the thin filaments and is the primary site where myosin binds to generate the force required for muscle contraction.

Tropomyosin

Tropomyosin is a regulatory protein that runs along the length of the actin filaments in a double helical structure. Its main function is to block the binding sites for myosin on actin in the absence of a contraction signal, thereby preventing unwanted muscle contractions.

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