A. Acts mainly on liver cells B. Stimulate glycogenolysis C....

A. Acts mainly on liver cells B. Stimulate glycogenolysis C. Stimulate gluconeogenesis D. Reduces glucose uptake and utilization Which of the following is correct about the action of glucagon from the above statements? (a) $\mathrm{A}$ and $\mathrm{B}$ only (b) B and C only (c) $\mathrm{A}, \mathrm{B}$ and $\mathrm{C}$ only (d) All of these

A. Acts mainly on liver cells
B. Stimulate glycogenolysis
C. Stimulate gluconeogenesis
D. Reduces glucose uptake and utilization Which of the following is correct about the action of glucagon from the above statements?
(a) $\mathrm{A}$ and $\mathrm{B}$ only
(b) B and C only
(c) $\mathrm{A}, \mathrm{B}$ and $\mathrm{C}$ only
(d) All of these

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Key Concepts

Glucagon

Glucagon is a peptide hormone produced by the pancreatic alpha cells that plays a crucial role in energy metabolism. It acts mainly on liver cells to raise blood glucose levels during fasting states by stimulating processes like glycogenolysis and gluconeogenesis.

Glycogenolysis

Glycogenolysis is the metabolic process wherein glycogen stored in the liver is broken down into glucose. This process is stimulated by glucagon and is essential for rapidly increasing blood glucose levels when they fall.

Gluconeogenesis

Gluconeogenesis is the biochemical pathway that synthesizes glucose from non-carbohydrate precursors such as lactate, glycerol, and amino acids. Glucagon stimulates this process in the liver, ensuring a continuous supply of glucose during prolonged periods without food.

Liver Metabolism Regulation

The liver is the central organ for regulating blood glucose through various metabolic pathways. It responds to hormonal signals like glucagon by engaging in glycogenolysis and gluconeogenesis while simultaneously reducing glucose uptake and utilization, thereby ensuring adequate glucose availability during fasting states.

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