Question

A leaflet enclosed with a vial containing $6,000,000$ units of penicillin G sodium states, "When $30 \mathrm{~mL}$ of sterile diluent are added the dry powder resulting concentration is 250,000 units $/ \mathrm{mL}$." Based on this information, how many milliliters of sterile water for injection should be used in preparing the following prescription? $\mathrm{R}$ Penicillin G potassium 6000,000 units Water for injection ad Q.S. Prepare a solution to contain 600,000 units $/ \mathrm{mL}$ Sig. $1 \mathrm{~mL}=600,000$ units of penicillin $\mathrm{G}$ sodium

   A leaflet enclosed with a vial containing $6,000,000$ units of penicillin G sodium states, "When $30 \mathrm{~mL}$ of sterile diluent are added the dry powder resulting concentration is 250,000 units $/ \mathrm{mL}$." Based on this information, how many milliliters of sterile water for injection should be used in preparing the following prescription?
$\mathrm{R}$
Penicillin G potassium 6000,000 units
Water for injection ad Q.S.
Prepare a solution to contain 600,000 units $/ \mathrm{mL}$
Sig. $1 \mathrm{~mL}=600,000$ units of penicillin $\mathrm{G}$ sodium

Essential Math and Calculations for Pharmacy Technicians

Indra K. Reddy,… 1st Edition

Chapter 11, Problem 1

Instant Answer

Step 1

Given that 1 mL of the final solution contains 600,000 units of penicillin G potassium, we need to prepare a solution with a concentration of 600,000 units/mL. Therefore, the total volume of the final solution needed can be calculated as: Volume = Total units / Show more…

Show all steps

Thanks for your feedback!

A leaflet enclosed with a vial containing $6,000,000$ units of penicillin G sodium states, "When $30 \mathrm{~mL}$ of sterile diluent are added the dry powder resulting concentration is 250,000 units $/ \mathrm{mL}$." Based on this information, how many milliliters of sterile water for injection should be used in preparing the following prescription? $\mathrm{R}$ Penicillin G potassium 6000,000 units Water for injection ad Q.S. Prepare a solution to contain 600,000 units $/ \mathrm{mL}$ Sig. $1 \mathrm{~mL}=600,000$ units of penicillin $\mathrm{G}$ sodium

Play audio

Feedback

Labs

Want to see this concept in action?

NEW

Explore this concept interactively to see how it behaves as you change inputs.

View Labs

Key Concepts

Reconstitution of Powdered Drugs

Reconstitution is the process of adding a liquid diluent to a powdered drug to create a solution or suspension with a specific concentration. Accurate reconstitution is critical to ensure that the medication is effective and safe, as it directly affects the dose administered.

Prescription Compounding

This concept covers the calculations and practical steps required to prepare a medication according to a specific prescription. It involves determining the final volume and the proper amount of diluent required to achieve the target concentration, ensuring that each measured dose contains the correct amount of active ingredient.

Concentration Calculation

This concept involves determining the amount of active ingredient per unit volume by dividing the total available drug units by the final desired volume. It ensures that the resulting solution has the prescribed concentration, which is essential for proper dosing.

Please give Ace some feedback