00:01
So for this question, we're given the following two molecules, and we're asked to start from the molecule here on the left and to propose a synthesis for the molecule on the right.
00:13
So whenever i am beginning to approach multi -step synthesis problems, i like to look at the similarities and differences and the different bonds that have broken and formed in the product, our final product, and our beginning molecule to give myself some clues as to the kinds of reactions that i need to include.
00:39
So if i look at my starting molecule, i see that i have broken this bond and i have formed this bond.
00:54
And i also notice that there is an inversion of stereochemistry here at this stereo center.
01:05
But all else about the molecule is similar.
01:09
So this tells me that i probably need to have some type of s -n -2 mechanism with c -n -minus as a nucleophile because i see an inversion of stereochemistry.
01:36
I'm going to start with this compound...