Consider the following statements: (1) racemic forms are not...

Consider the following statements: (1) racemic forms are not optically active but are resolvable (2) the presence of chiral atom is sufficient but not the necessary condition for enantiomer (3) meso compounds are inactive and are not resolvable (4) conformational enantiomers can be resolved Nuw select the conrect statements. (a) 1,2 and 3 (b) 2,3 and 4 (c) 1,2 and 4 (d) $1,2,3$ and 4

Consider the following statements:
(1) racemic forms are not optically active but are resolvable
(2) the presence of chiral atom is sufficient but not the necessary condition for enantiomer
(3) meso compounds are inactive and are not resolvable
(4) conformational enantiomers can be resolved
Nuw select the conrect statements.
(a) 1,2 and 3
(b) 2,3 and 4
(c) 1,2 and 4
(d) $1,2,3$ and 4

Key Concepts

Conformational Isomerism

Conformational isomers (or conformers) are different spatial orientations of a molecule that can be interconverted by rotations around single bonds. Although they can be enantiomeric in cases where different conformations cannot be superimposed, these interconversions are typically rapid at room temperature, making the resolution of such conformational enantiomers impractical under normal conditions.

Meso Compounds

Meso compounds are molecules that contain multiple stereocenters but have an internal plane of symmetry, making them overall achiral and optically inactive. Due to their symmetry, enantiomers are not present, and hence they do not exhibit the ability to be resolved into separate enantiomers using methods that rely on chirality.

Racemic Mixtures

A racemic mixture is a 1:1 combination of two enantiomers, which, although each individual enantiomer is optically active, their equal mixture results in no net optical activity. Such mixtures can be resolved into their individual enantiomers using various separation techniques because their physical properties may differ under chiral environments.

Chirality and Enantiomerism

Chirality refers to the geometric property where a molecule is not superimposable on its mirror image. The presence of a chiral center (or stereogenic center) is sufficient to produce chirality, but it is not strictly necessary; molecules can be chiral due to the arrangement of atoms and overall asymmetry even in the absence of a classic chiral center. Enantiomers are pairs of chiral molecules that are non-superimposable mirror images of each other.

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