Question
Diagram the mechanism of RNase T1 (or T2) action. Because this is the same mechanism used in base hydrolysis, how does this explain why DNA is not subject to base hydrolysis?
Step 1
RNase T1 is an endonuclease that specifically cleaves RNA at the 3' side of guanosine residues. It has a specific active site that facilitates the hydrolysis of the phosphodiester bond in RNA. Show more…
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