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Drug pharmacokinetics The level of medication in the bloodstream after a drug is administered is often modeled by a function of the form$$S(t)=A t^{p} e^{-k t}$$where $A, p,$ and $k$ are positive constants. This is called a surge function because its graph shows an initial surge in the drug level followed by a more gradual decline. (Particular cases have been investigated in Example 9 and Exercise 4.2.51.)(a) Use l'Hospital's Rule to show that lim $_{t \rightarrow \infty} S(t)=0$ for all positive values of $A, p,$ and $k .$(b) Investigate the family of surge functions for $A=1$ and positive values of $p$ and $k .$ What features do these curves have in common? How do they differ from one another? In particular, what happens to the maximum and minimum points and inflection points as $p$ and $k$ change? Illustrate by graphing several members of the family.
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Calculus 1 / AB
Chapter 4
Applications of Derivatives
Section 3
L'Hospital's Rule: Comparing Rates of Growth
Differentiation
Missouri State University
Campbell University
Baylor University
University of Michigan - Ann Arbor
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So we have our love. It'll form. Oh, so we come. You can be friendship. That So you have Lobito. Well, you're gonna help. Unease, But here we're not Differentiate that. So you're gonna get in, Comes he this one a time. So all the cake, um, zone from differentiating made today when you have this form Also, you get these expressions. Oh, employees in t going to be ready. So where astronomers thesis positive he may have one. It's positive. Well, this is gonna go to Katie. And also, all these goes also, baby. So we have also a logical farm. But ah, well, we can do local again, but not this year. That, uh, with the do a pli love till again. What you want would get a sophomore a friendship in that you're gonna get James team like this one, huh? You could have power be my costume over on down world, and you get a king squares. Okay, that's Kate. Square a Get tea. So we'll get this form that here were decreasing the power. Oh, often hear the bar of tea This be to the whiteness do. Whereas here it was a B minus one. We said it would just be so We're going decreasing in Power's off. He added. Step here. Where us? Here for day. For days. The Terminator, the borough, The experiential remains the same. So we'll, uh, at some point you're gonna get that B minus some into your number. It's gotta be mortar than zero. So that that would bring the power off t down. And then you get something off the farm ghostlike a first t e t the guns. So what's he goes to infinity here? This expression is gonna go to some constant or anything. So I'm gonna go to Syria. Um, so, uh oh, you don't know obstructed strictly of which point we will stop. But definitely there's gonna be some point. We're get something over form from Causton, but by an exponential. So Oh, but let's you conclude that he's I mean it. These people, it's you. So uh, was expected. Well, they get a time go to Haiti. The drug concentration in the blood I should go, is you and then we'll you differentiate dysfunction. You want to pump your buddies this prime? She she for taking a beagle to want to have Do you be These are functioning grips Exponential Linus K t we want to. The friendship is So you have a burger too? Happy p and T being with this one comes there. Exponential. So these parts accounts for differentiating the deep part Now for differentiating exponential, you know, half well differentiated An exponential gives you exponential again. But since we have ah, another function, you know, and thereby the channel you get my musky So these have you shocked us? Well, as you can see deep, it'd be here. Come here. Eating us tea hands. He did it be wearing this one so that we can fucked her that ticket game. I just wanna hear, Hear the right. These function of E in line is key. He Misty, Wait this one. And in that times, mostly here you have. Ah, why this Katie, uh, bless people blows. So, uh well, as you can see from here, all this will be always possible. He saw it was busted. So if prime or you make ready from determined by the side of these so well, if kmp are positive if prime will affinity for Thio be here Well okay. So is that determines their Where is that mark? Smart like should look something like grazes which is a much mind grease is with this point being okay on their four day inflection points you want to compute? What he's is no crime to look at were were they uncovered changes. So for his little crime, it's easier to differentiate his expression. Some function expresses this. I'm off those functions. Uh, they're here on your friendship. These? Oh, you differentiating friend shaking First day power functions will be and being like this one Then you grease the power off t buy one Does get you know d to the boat off being witness to times your exponential. I know when we differentiating way differentiate Hobart dysfunction explanation. She'll be here minus K A minus K comes from the inner reality here to mine escaped and speed James. He did a team. I was one. That's the exponential. So now we want the differential. This part. So you differentiating this part well, First friendship the power functions where you get out. Oh Waas Also there is someone there Some witness key then spew from the power on the guns. He might want the exponential. You might just kill you d You didn't might miss Katie. I know we want to differentiate the exponential here. So you're gonna get oh, my nose. Okay. Damn something or minus case of the That gives you last case, squirt. Damn Stevie for you. Yeah, my nose. Okay. Do you? So to write these you Perhaps I'm easier for we can fuck through the exponential Sze, right? Is that? Come on, doctor. There. So we have Yeah, to the minus key. And as you can see there, the lowest power off is Peter my store. All right, so So you can write Jesus. He's square times. He did it. P minus stool. This board that I'm this polar like tea. I'm Steve today. He might still from the same for the sport, so that well, Dr Dennis Dee, put a B minus two. I'm being that multiplying the Polina meal. Ah, well, see, comes know this part. Good. That speech was one No, no, for this part also, that accounts for it team. So we'll let you get you here. There is minus K p minus cape you so minus two times keeping that to the boy off team because he's one of us. That fucker on in here, So plus k square square, plus Okay. Squared, squared. So these are secondly relative. So was you can see here it's gonna be gonna give up 40 going to infinity. So look, some from base give up. But it's gonna be some point. We've seen what's going down Cooking up, determined by over the zeros for this building on Mel Uh, so looking dead your friend grasps. Well, you can see here, here for the green Want we have X Be ableto for the green one, people toe 0.15. I'm, uh, Katie's minus one case one. So for this green one, you see that there's inflection points like there. I'm there with these green one will be friction. Points are for part of what a black one in kitchens get your points are pushed further, uh, on, uh, all day one for the red one. Is this Well, no collection points like, Oh, there, there for that red one. Piece. 15 Okay, she got one. So going back to what is little prime? Just, uh Well, we're the serious for this bull, you know? You know these? He took the d a. Go to one from these, uh, expression
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