00:01
So we want to describe how protocells might have formed, and we need to take into account hydrophilic and hydrophobic interactions.
00:10
Okay, so to have a protocell, you need some kind of isolation, right? you need a membrane.
00:16
So membrane formation is the most important bit here.
00:19
And that's going to form spontaneously from lipids, particularly fatty acids very early on, rather than phospholipids.
00:28
So remember that fatty acids have hydrophobic regions, hydrophobic regions.
00:38
And these hydrophobic regions will preferentially not be facing outwards into environments or inwards into the aqueous solution within the protocell.
00:47
They would want to be facing each other.
00:49
And that's why we get bilayer formation.
00:52
So we get the membrane formation.
00:55
And then next, something else that is important...