For children, heparin sodium is administered by intermittent...

For children, heparin sodium is administered by intermittent IV infusion in a range of 70 to 85 units/kg of body weight every $6 \mathrm{hrs}$. For a $68-\mathrm{lb}$ child, calculate the range, in $\mathrm{mL}$, of a heparin sodium injection containing $1000 \mathrm{units} / \mathrm{mL}$ to be administered daily.

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Key Concepts

Concentration and Volume Conversion

Medications are often provided in specific concentrations, such as 1000 units/mL. Converting the calculated dose in units to a volume in milliliters involves dividing the total units by the concentration. This conversion is necessary to accurately measure the dose that will be administered during each infusion.

Frequency of Administration and Total Daily Dose Calculation

When a medication is given at regular intervals, such as every 6 hours, it means multiple doses are administered per day. Calculating the total daily dose involves multiplying the single dose amount by the number of administrations per day, ensuring that the cumulative dose meets therapeutic requirements.

Weight Conversion

This concept involves converting a patient’s body weight from one unit to another, usually from pounds to kilograms. Since many dosages are prescribed per kilogram of body weight, accurate conversion is essential to ensure proper dosage calculation.

Dose Calculation Based on Body Weight

Dosage calculations that use units per kilogram require multiplying the patient’s weight in kilograms by the prescribed dosage (e.g., 70 to 85 units/kg). This calculation ensures that the amount of medication administered is proportional to the patient's size, optimizing efficacy while minimizing potential risks.

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