For the pedigree shown here, the disorder is caused by a...

For the pedigree shown here, the disorder is caused by a recessive (g) autosomal allele. Label each of the following individuals with the correct genotype $[G G, G g, g g]$
a. Generation I, number 2
b. Generation II, number 1
c. Generation II, number 2
d. Generation III, number 3

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Key Concepts

Recessive Alleles

Recessive alleles are those that require an individual to have two copies (homozygous recessive) for the associated trait or disorder to be expressed. Individuals with one dominant and one recessive allele (heterozygous) typically do not exhibit the trait but can pass the recessive allele to their offspring.

Pedigree Analysis

Pedigree analysis involves evaluating family trees to understand how traits and disorders are inherited across generations. It is used to deduce the genetic status of individuals based on observable traits and known inheritance patterns, often identifying carriers and affected individuals.

Autosomal Inheritance

Autosomal inheritance refers to genes that are located on the autosomes (non-sex chromosomes). This means that traits associated with these genes are inherited similarly by both men and women, without the influence of sex-linked patterns.

Genotype Inference

Genotype inference is the process of determining an individual’s genetic makeup by analyzing the family pedigree and understanding Mendelian genetics. This includes deducing whether individuals are homozygous dominant, heterozygous (carriers), or homozygous recessive based on the pattern of trait manifestation in the pedigree.

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