How many milliliters of methotraxate suspensions containing 260 mg and 400 mg per mL should be u

Name: Problem 29, Chapter 7: Essential Math and Calculations for Pharmacy Technicians
Uploaded: 2023-06-14T16:40:42-08:00
Channel: Gayathri Janakiraman Paramasivan
Description: How many milliliters of methotraxate suspensions containing 260 mg and 400 mg per mL should be used in preparing 1000 mL of a suspension containing 30 % of methotraxate?

step 1 question we need to dissolve antibiotics to create a liquid form but this is to be done in certa

Question

How many milliliters of methotraxate suspensions containing $260 \mathrm{mg}$ and $400 \mathrm{mg}$ per $\mathrm{mL}$ should be used in preparing $1000 \mathrm{~mL}$ of a suspension containing $30 \%$ of methotraxate?

   How many milliliters of methotraxate suspensions containing $260 \mathrm{mg}$ and $400 \mathrm{mg}$ per $\mathrm{mL}$ should be used in preparing $1000 \mathrm{~mL}$ of a suspension containing $30 \%$ of methotraxate?

Essential Math and Calculations for Pharmacy Technicians

Indra K. Reddy,… 1st Edition

Chapter 7, Problem 29

Instant Answer

Solved by Expert Gayathri Janakiraman Paramasivan

06/14/2023

Step 1

Since the final solution is to contain 30% methotrexate, the amount of methotrexate needed is 30% of 1000 mL: $1000 \mathrm{mL} \times 0.30 = 300 \mathrm{mg}$ Show more…

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How many milliliters of methotraxate suspensions containing $260 \mathrm{mg}$ and $400 \mathrm{mg}$ per $\mathrm{mL}$ should be used in preparing $1000 \mathrm{~mL}$ of a suspension containing $30 \%$ of methotraxate?

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Key Concepts

Mixture Problems

These are problems that involve combining substances with different concentrations to achieve a desired final concentration. They typically require setting up equations based on the conservation of mass or the amount of the active ingredient and solving for the unknown quantities.

Mass/Volume Concentration

This concept describes the amount of solute, measured in mass units (like milligrams), present in one unit volume of solution (such as a milliliter). It is a key parameter in determining how potent a solution is and is essential when preparing solutions with precise dosage requirements.

Alligation Method

This is a traditional technique used in pharmacy and chemistry to determine the correct proportions of solutions with differing concentrations to mix together to obtain a solution of a desired concentration. It simplifies the process of solving mixture problems without needing to set up detailed algebraic equations.

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