Question
In light of your answer to Problem $11-74,$ explain why one of the following isomers undergoes E2 reaction approximately 100 times as fast as the other. Which isomer is more reactive, and why?
Step 1
In an E2 reaction, the hydrogen and the leaving group (in this case, chlorine) are eliminated in a single step, and this requires them to be in an anti-periplanar geometry. This means that they must be on opposite sides of the molecule and in the same plane. Show more…
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