In Problems 43-50, use properties of determinants to find the value of each determinant if it is known that
$$
\left|\begin{array}{llr}
x & y & z \\
u & v & w \\
1 & 2 & 3
\end{array}\right|=4
$$
$\left|\begin{array}{ccc}1 & 2 & 3 \\ x-u & y-v & z-w \\ u & v & w\end{array}\right|$