Mice lacking a gene for fibronectin do not survive early embryonic development. Name two process

Mice lacking a gene for fibronectin do not survive early...

Key Concepts

Cell Adhesion

Cell adhesion refers to the mechanism by which cells attach to one another and to the surrounding extracellular matrix. This process is essential during embryonic development for the organization of cells into tissues and maintenance of tissue architecture. Adhesion molecules like fibronectin play critical roles in facilitating these cell-to-cell and cell-to-matrix interactions.

Cell Migration

Cell migration is the orchestrated movement of cells from one position to another, a fundamental aspect of embryonic development. This process is vital for proper tissue formation and morphogenesis, as cells must travel to specific locations to build organs and structures. Fibronectin provides guidance and support for migrating cells by interacting with integrin receptors, thus ensuring that cells move correctly during development.

Transcript

00:01 Other students today we're going to be answering this question in regards to a chapter on interaction between cells and their environment.

00:10 And the question here reads saying that my status lacking in gene for fibro nectin.

00:21 Do not survive early embryonic development.

00:26 Please name the two processes that might be disrupted.

00:30 And such embryos.

00:33 So what is fibroenectin? fibroenctin, sorry if i can mispronounce those words, is a high molecular weight, glycol protein of an extracellular matrix that binds to membrane -span receptors, proteins called integrants.

00:57 And i'm sorry if i mispronounce that also, also, because if you watch my videos, if you have watched my videos or your news of this channel, this is a common occurrence where i'm going to keep butchering these words, no matter how hard.

01:14 I try to study them, i'm going to keep messing them up.

01:17 But in who, nothing about my fumbles.

01:20 Let's get through the fibrone neck dins.

01:26 They also bind to other extracellular matrix proteins such as collagen fibrin and hyperin sulfate protein glycans which is also an example of that would be sindincans and i sorry if i butcher that too sorry if i missed that too but what's the function of the fibroeniction.

02:04 Their specific domains allow fibronections to promote cell -to -cell adhesion, cell to basement membrane attachment, clot stabilization, embryogeneticis, i mean, embryogenis, nervous regeneration, fibroblast migration, microphase function pathogens, which are like your virus, fungus, bacteria, and protozoas, binding to mammalian.

02:51 Sorry if i put you that, mispronounce a word that should have been easy for me to pronounce mammalial cells and extracellular matrix...

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