00:01
Mutations in which of these tumor suppressor genes causes retinoblastoma.
00:07
Is it p21, the ras proteins, rb, or tgf, the beta? so we have transforming growth factor beta.
00:21
So this, so this one, d, this one can, it stops the cell cycle at g1, and it helps decide if we're going to go forward with cell division or not.
00:32
So you can see why this is.
00:33
This would be a tumor suppressor.
00:35
We have p21, which is associated with, again, cell cycle arrest if dna damage is detected.
00:45
So again, you can see why this would be an important tumor suppressor...