Question

Normal physiologic defense mechanisms that exist to prevent disease from food and waterborne pathogens may be disrupted by which of the following? (A) Over-the-counter vitamin use. (B) $\mathrm{H}_2$ blockers and proton-pump inhibitors. (C) Foods treated with pesticides. (D) Extensive exercise.

   Normal physiologic defense mechanisms that exist to prevent disease from food and waterborne pathogens may be disrupted by which of the following?
(A) Over-the-counter vitamin use.
(B) $\mathrm{H}_2$ blockers and proton-pump inhibitors.
(C) Foods treated with pesticides.
(D) Extensive exercise.

Emergency Medicine Examination & Board Review

Susan Promes 3rd Edition

Chapter 13, Problem 15

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The question is asking about factors that can disrupt normal physiologic defense mechanisms against food and waterborne pathogens. The options are (A) Over-the-counter vitamin use, (B) $\mathrm{H}_2$ blockers and proton-pump inhibitors, (C) Foods treated with Show more…

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Normal physiologic defense mechanisms that exist to prevent disease from food and waterborne pathogens may be disrupted by which of the following? (A) Over-the-counter vitamin use. (B) $\mathrm{H}_2$ blockers and proton-pump inhibitors. (C) Foods treated with pesticides. (D) Extensive exercise.

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Key Concepts

Pharmacologic Acid Suppression

Medications such as H2 blockers and proton pump inhibitors reduce the secretion of gastric acid, thereby increasing the pH level in the stomach. This suppression can weaken the natural acid barrier, potentially allowing ingested pathogens to survive and colonize, leading to an increased risk of infections.

Gastric Acid Defense

Gastric acid serves as a crucial defense mechanism in the stomach by maintaining a low pH environment that helps destroy pathogens ingested with food and water, thereby reducing the likelihood of infections. This natural barrier prevents harmful bacteria and other organisms from thriving and causing gastrointestinal disease.

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