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Hi there.
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Today we're going to discuss intracellular signaling.
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So intracellular signaling is pretty special in that the signal molecule actually enters the cell to create a cellular response.
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So this starts with the reception process in which the signal, typically a molecule that is hydrophobic enough to move through the phospholipid bilase, or is just a small enough molecule that it can go through and binds to an intracellular receptor.
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So the receptor itself could be found in either the cytoplasm, as illustrated here, or it could be already residing in the nucleus, in which the signal would actually go through the nuclear membrane into the nucleus itself.
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So the receptor and signal forms a type of.
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Of complex that then moves into the nucleus if it's not in the nucleus already.
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And usually this complex is used to turn particular genes on or off.
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And the complex acts as a transcription factor to turn those genes on and off.
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And that's only when this receptor protein is activated with the signal...