Question
Replication and segregation of eukaryotic chromosomes require three functional elements: replication origins, a centromere, and telomeres. How would a chromosome be affected if it lacked (a) replication origins or (b) a centromere?
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In eukaryotes, there are multiple origins of replication on the chromosome to ensure that the entire length of the chromosome is replicated quickly. The centromere is a region of DNA typically found near the middle of a chromosome where two identical sister Show more…
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Replication and segregation of cukaryotic chromosomes require three functional elements: replication origins, a centromere, and telomeres. How would a chromosome be affected if it lacked (a) replication origins or (b) a centromere?
Multiple origins of replication (a) speed up replication of eukaryotic chromosomes (b) enable the lagging strands and leading strands to be synthesized at different replication forks (c) help to relieve strain as the double helix unwinds (d) prevent mutations (e) are necessary for the replication of a circular DNA molecule in bacteria
Describe the consequences that would arise if a eukaryotic chromosome: A. contained only one origin of replication: (i) at the exact center of the chromosome. (ii) at one end of the chromosome. B. lacked telomeres. C. lacked a centromere. Assume that the chromosome is 150 million nucleotide pairs in length, a typical size for an animal chromosome, and that DNA replication in animal cells proceeds at about 100 nucleotides per second.
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