Question

Since no molecular oxygen participates in the citric acid cycle, the steps in which acetyl groups are oxidized to $\mathrm{CO}_{2}$ involve removal of hydride ions and hydrogen ions. What is the acceptor of hydride ions? What is the acceptor of hydrogen ions?

Name: Problem 23, Chapter 21: Fundamentals of General, Organic, and Biological Chemistry
Uploaded: 2022-01-27T14:08:01-08:00
Duration: 2 min 3 s
Channel: Ramesh Singh
Description: Since no molecular oxygen participates in the citric acid cycle, the steps in which acetyl groups are oxidized to CO2 involve removal of hydride ions and hydrogen ions. What is the acceptor of hydride ions? What is the acceptor of hydrogen ions?

   Since no molecular oxygen participates in the citric acid cycle, the steps in which acetyl groups are oxidized to $\mathrm{CO}_{2}$ involve removal of hydride ions and hydrogen ions. What is the acceptor of hydride ions? What is the acceptor of hydrogen ions?

Fundamentals of General, Organic, and Biological Chemistry

John McMurry, David… 1st Edition

Chapter 21, Problem 23

Instant Answer

Solved by Expert Ramesh Singh

01/27/2022

Step 1

Step 1: The citric acid cycle, also known as the Krebs cycle, is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into adenosine triphosphate Show more…

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Since no molecular oxygen participates in the citric acid cycle, the steps in which acetyl groups are oxidized to $\mathrm{CO}_{2}$ involve removal of hydride ions and hydrogen ions. What is the acceptor of hydride ions? What is the acceptor of hydrogen ions?

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Key Concepts

NAD+ as an electron carrier

In cellular metabolism, NAD+ serves as a key coenzyme that accepts hydride ions (H–) during oxidation reactions. When NAD+ accepts a hydride ion, it is reduced to NADH, a process essential for transferring reducing equivalents into the electron transport chain for ATP production.

Proton (H+) release in redox reactions

During oxidative reactions, hydrogen atoms are often removed as their components: a hydride ion and a proton. While the hydride ion is specifically captured by NAD+, the hydrogen ion (H+) is typically released into the surrounding medium, contributing to the formation of a proton gradient that later drives ATP synthesis.

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