The process by which neutrophils squeeze through capillary walls in response to inflammatory sig

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The process by which neutrophils squeeze through capillary...

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Key Concepts

Diapedesis

Diapedesis is the process by which white blood cells, particularly neutrophils, actively squeeze through the endothelial cell junctions of capillary walls in response to inflammatory signals. This mechanism is vital for allowing immune cells to exit the bloodstream and migrate into tissues where they can address infections or injury.

Neutrophils

Neutrophils are a type of white blood cell that are key players in the innate immune response. They are among the first cells to arrive at sites of inflammation, where they help neutralize pathogens and initiate the healing process through mechanisms such as phagocytosis and the release of antimicrobial substances.

Inflammatory Response

The inflammatory response is a complex biological reaction to tissue injury or infection. It involves the release of chemical signals like cytokines and chemokines, which not only promote vasodilation and increased vascular permeability but also facilitate the recruitment and migration of immune cells, such as neutrophils, to the affected site.

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