Question

Using a vial containing 300,000 units of penicillin $G$ potassium, how many milliliters of sterile water for injection should be added to the dry powder in preparing a solution having a concentration of 30,000 units $/ \mathrm{mL}$ ?

   Using a vial containing 300,000 units of penicillin $G$ potassium, how many milliliters of sterile water for injection should be added to the dry powder in preparing a solution having a concentration of 30,000 units $/ \mathrm{mL}$ ?
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Essential Math and Calculations for Pharmacy Technicians
Essential Math and Calculations for Pharmacy Technicians
Indra K. Reddy,… 1st Edition
Chapter 11, Problem 5 ↓

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Given that the desired concentration is 30,000 units/mL.  Show more…

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Using a vial containing 300,000 units of penicillin $G$ potassium, how many milliliters of sterile water for injection should be added to the dry powder in preparing a solution having a concentration of 30,000 units $/ \mathrm{mL}$ ?
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Key Concepts

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Solution Concentration
This concept involves understanding how the concentration of a solution is defined as the amount of solute per unit volume of solution. It is a fundamental idea in pharmacy where the dosage and efficacy of a drug depend on accurately preparing solutions with specified concentrations.
Dilution Calculation
Dilution calculation is the process used to determine the required volume of solvent to add to a given amount of solute in order to achieve a desired concentration. This typically involves dividing the total amount of solute by the target concentration, thereby ensuring that the final solution contains the correct proportion of the active ingredient per unit volume.
Pharmaceutical Reconstitution
Pharmaceutical reconstitution refers to the process of converting a powdered medication into a liquid form by adding an appropriate amount of diluent. This procedure is critical for ensuring safe and effective drug administration, as it allows for the precise measurement of dosage based on the concentration achieved through proper dilution.

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The drug vial contains 1,000,000 units of penicillin G. The label directions state: Add 2.3 ml of sterile water to the vial and 0.6 ml = 250,000 units. How many milliliters equal 600,000 units? 0.01 ml 1.4 ml 14.4 ml .14 ml 144 ml

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A 5,000,000 units penicillin G potassium vial requires 23 mL of diluent be added to the dry powder to result in a 200,000 units/mL concentration. How much diluent must be added to make a final concentration of 500,000 units/mL?

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