00:01
Okay, in order to answer this question, let's talk about the electron transport chain.
00:04
Remember that during metabolism, there is going to be production of nadh and fadh 2 molecules that are electron carriers.
00:13
It means they are going to transport electrons from metabolism, okay? and they are going to unload these electrons to the electron transport chain that is located in the mitochondria.
00:24
Imagine this is the mitochondria.
00:27
It has two membranes.
00:29
It has this membrane that is the outer mitochondrial membrane, and also it has an inner mitochondrial membrane.
00:38
This place here is called the mitochondrial matrix, and this place between the outer inner mitochondrial matrix is called the intermembranose space.
00:49
So here in the inner mitochondal matrix, we have the electron transport chain that is made of for complexes.
00:55
Complex number one, complex number two, three, and four.
00:57
And adh is going to donate the electrons to complex number one, while fadh2 is going to be the same, but in complex number two.
01:08
Okay, and once electrons get there, they are going to flow or to move to complex number three and then to complex number four, where they are going to react with oxygen producing in water.
01:20
But what is the purpose of this? well, the purpose of this is that as electrons are going to flow through this, electron transport chain, it is going to power active transport pumps that are going to pump protons, well, not here, because protons don't move through complex number two, but in complex number one, three and four, protons are going to move from the mitochondrial matrix to the intermembron space, and there is going to have to create a gradient, practically, of high protons levels here in the intermembrances space and low proton levels in the mitochondrial matrix.
02:03
Okay, so because of this gradient of concentration, protons are going to move, are going to move back to the matrix because of gradient in order to have like equal amounts of protons there in both compartments.
02:19
However, this inner mitochondrial membrane is not permeable to protons...