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What is the percentage concentration of cocaine $\mathrm{HCl}$ required to make an isotonic solution?
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The molecular weight of cocaine HCl is 339.81 g/mol. Show more…
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Cocaine $\left(\mathrm{C}_{17} \mathrm{H}_{21} \mathrm{O}_{4} \mathrm{~N}\right)$ is a natural substance found in $\operatorname{coca}$ leaves, which have been used for centuries as a local anesthetic and stimulant. Illegal cocaine arrives in the United States either as the pure compound or as the hydrochloride salt $\left(\mathrm{C}_{17} \mathrm{H}_{21} \mathrm{O}_{4} \mathrm{NHCl}\right)$. At $25^{\circ} \mathrm{C},$ the salt is very soluble in water $(2.50 \mathrm{~kg} / \mathrm{L}),$ but cocaine is much less so $(1.70 \mathrm{~g} / \mathrm{L})$ (a) What is the maximum mass (g) of the hydrochloride salt that can dissolve in $50.0 \mathrm{~mL}$ of water? (b) If the solution from part (a) is treated with $\mathrm{NaOH}$, the salt is converted to cocaine. How much more water (L) is needed to dissolve it?
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