Which is not a characteristic of a person with cystic fibrosis? A. chloride channel defect B. di

step 1 Okay, so this problem wants to know which of the following list of characteristics is not a char

Which is not a characteristic of a person with cystic...

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Key Concepts

Cystic Fibrosis

Cystic fibrosis is a genetic disorder that affects various organs, particularly the lungs and digestive system. It is caused by mutations in the CFTR gene, which lead to the production of abnormally thick and sticky mucus. This abnormal mucus interferes with normal organ function and predisposes individuals to recurrent infections and digestive issues.

Chloride Channel Defect

A defect in chloride channels is a defining feature of cystic fibrosis. Mutations in the CFTR gene disrupt the normal transport of chloride ions across cell membranes, leading to imbalances in salt and water movement. This disruption is central to the disease's manifestations, affecting both pulmonary and gastrointestinal functions.

Respiratory Complications

One of the major clinical manifestations of cystic fibrosis is the occurrence of recurrent lung infections. The thick mucus in the airways provides a suitable environment for bacteria to grow, leading to chronic respiratory issues and inflammation which can significantly impair lung function.

Digestive Problems

Digestive problems are common in cystic fibrosis due to the blockage of pancreatic ducts by thick mucus. This obstruction prevents the proper secretion of digestive enzymes, leading to malabsorption, nutrient deficiencies, and gastrointestinal complications.

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