00:01
Okay, in order to answer this question, let's talk about antigen presenting cells.
00:06
Okay, for example, let's suppose here we have skin, your skin, okay? and there is an injury here.
00:12
It is an injury.
00:13
Remember that normally skin is a physical barrier for pathogens, okay? but as there is an injury here, an injury, then some pathogens can enter, like through skin, into our body, okay? so these pathogens, let's suppose this is a pathogen, they have many like proteins or glycoproteins like on their surface, okay? and they are going, these, this surface molecules or molecules like that are, or that belong to these pathogens are going to be essential for antigen presentation.
00:51
Because once they enter, some macrophages are going to be present here.
00:57
This is a macrophage and it is going to phagocitate in this pathogen.
01:01
Here.
01:03
It's going to phagoside this, this pathogen, and it is going to digest this pathogen, okay? and some of these proteins are part of this pathogen are going to be called antigens, and they are going to be expressed, like on the surface of this macrophage.
01:26
See, like this, as suppose, this is going to be the antigen that is going to be expressed, like from this pathogen, okay? and this is important because this, this, this, this, this are going to, for example, suppose it is a macrophage, okay? they are going to present this antigen to more advanced cells...