Which of the following is TRUE of necrotizing fasciitis? (A)...

Which of the following is TRUE of necrotizing fasciitis?
(A) It is characterized by widespread necrosis involving the subcutaneous tissue and fascia.
(B) It often involves underlying muscle.
(C) Treatment of choice is medical management.
(D) It is usually caused by a single organism.

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Key Concepts

Microbial Etiology

Necrotizing fasciitis can be caused by either a single organism (monomicrobial) or by multiple organisms (polymicrobial). The distinction is important for guiding antibiotic therapy, as polymicrobial infections are particularly common and require broad-spectrum treatment.

Treatment Approach

The treatment of necrotizing fasciitis is primarily surgical rather than purely medical. Aggressive surgical debridement of the necrotic tissues, often in combination with broad-spectrum antibiotics, is the management of choice, underscoring the importance of prompt and decisive intervention.

Tissue Involvement

The infection primarily affects the subcutaneous tissues and fascia, with necrosis being a hallmark of the disease. While underlying muscle can be involved, it is not typically the primary target, which is a key distinguishing factor.

Necrotizing Fasciitis

Necrotizing fasciitis is a life-threatening, rapidly spreading infection that results in widespread necrosis of the fascial planes and subcutaneous tissues. Its aggressive nature and high mortality rate make early diagnosis and prompt intervention critical.

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