Which of the following statements about brucellosis is...

Which of the following statements about brucellosis is false? a) Fevers that come and go over a long period of time gave it the name "undulant fever." b) The causative agent can infect via mucous membranes. c) The causative agent is readily killed by phagocytes. d) The disease in cattle is characterized by chronic infection. e) Butchers are advised to wear goggles or a face shield to help protect against the disease.

Which of the following statements about brucellosis is false?
a) Fevers that come and go over a long period of time gave it the name "undulant fever."
b) The causative agent can infect via mucous membranes.
c) The causative agent is readily killed by phagocytes.
d) The disease in cattle is characterized by chronic infection.
e) Butchers are advised to wear goggles or a face shield to help protect against the disease.

Key Concepts

Intracellular Survival and Phagocyte Evasion

A key aspect of Brucella bacteria is their ability to survive and replicate within host phagocytic cells. This intracellular survival mechanism allows Brucella to evade destruction by the immune system, contributing to persistent and chronic infections, which is why the assertion that they are readily killed by phagocytes is incorrect.

Brucellosis

Brucellosis is a zoonotic infection caused by Brucella bacteria, which typically affects both humans and animals. It is characterized by nonspecific symptoms such as fever, malaise, and fatigue, and in animals, it often leads to reproductive issues like infertility or abortion. Its diagnosis and management are important in both clinical and veterinary settings.

Undulant Fever

Undulant fever is a clinical hallmark of brucellosis characterized by fevers that wax and wane over extended periods. This pattern of fever is due to the intermittent nature of the bacterium's presence and replication within the host, making it a useful diagnostic clue in identifying the infection.

Zoonotic Transmission and Occupational Risks

Brucellosis is primarily transmitted from infected animals to humans through direct contact with contaminated animal products, inhalation, or via mucous membranes. This is particularly relevant for individuals in high-risk occupations such as veterinarians, farmers, or butchers, who are advised to use protective gear including gloves, face shields, or goggles to minimize exposure.

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