Which of the following statements is true? a. The gene...

Name: Problem 14, Chapter 8: Essentials of Biology
Uploaded: 2021-03-15T18:50:04-08:00
Duration: 3 min 38 s
Channel: Christina Sorrentino
Description: Which of the following statements is true? a. The gene product of a proto-oncogene inhibits the cell cycle. b. Proto-oncogenes are mutant versions of oncogenes that cause cancer. c. When mutated tumor suppressor genes lose their function, cancer may result. d. When tumor suppressor genes mutate, they become oncogenes. e. All of these are correct.

Which of the following statements is true? a. The gene product of a proto-oncogene inhibits the cell cycle. b. Proto-oncogenes are mutant versions of oncogenes that cause cancer. c. When mutated tumor suppressor genes lose their function, cancer may result. d. When tumor suppressor genes mutate, they become oncogenes. e. All of these are correct.

Which of the following statements is true?
a. The gene product of a proto-oncogene inhibits the cell cycle.
b. Proto-oncogenes are mutant versions of oncogenes that cause cancer.
c. When mutated tumor suppressor genes lose their function, cancer may result.
d. When tumor suppressor genes mutate, they become oncogenes.
e. All of these are correct.

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Key Concepts

Mutation and Cell Cycle Regulation

The integrity of the cell cycle is maintained by a balance between oncogenes, which promote cell growth, and tumor suppressor genes, which inhibit unchecked proliferation. Mutations affecting either group can disrupt this balance, leading to abnormal cell division and an increased risk of cancer formation.

Tumor Suppressor Genes

Tumor suppressor genes encode proteins that help control cell division, promote DNA repair, and induce cell death when necessary. These genes act as safeguards to prevent uncontrolled cell proliferation. When tumor suppressor genes are mutated and lose their function, their inability to regulate the cell cycle can lead to the development of cancer.

Proto-oncogenes and Oncogenes

Proto-oncogenes are normal genes that play crucial roles in cell growth and division. When these genes undergo mutations or are aberrantly activated, they can become oncogenes, contributing to uncontrolled cellular proliferation and cancer. The transformation from proto-oncogene to oncogene is a key event in the molecular basis of cancer.

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