Which of these statements concerning peptide bonds is FALSE?...

Which of these statements concerning peptide bonds is FALSE? (A) Their formation involves a reaction between an amino group and a carboxyl group. (B) $\quad$ They are the primary bonds that hold amino acids together. (C) $\quad$ They have partial double bond character. (D) Their formation involves hydration reactions.

Which of these statements concerning peptide bonds is FALSE?
(A) Their formation involves a reaction between an amino
group and a carboxyl group.
(B) $\quad$ They are the primary bonds that hold amino acids
together.
(C) $\quad$ They have partial double bond character.
(D) Their formation involves hydration reactions.

Key Concepts

Hydrolysis Reaction

Hydrolysis is the process that breaks peptide bonds by the addition of water. Instead of being used to form peptide bonds, water reacts with and cleaves these bonds, effectively reversing the condensation reaction that created them.

Resonance and Partial Double Bond Character

Due to resonance, the peptide bond exhibits partial double bond character between the carbon and nitrogen atoms. This stabilizes the peptide bond, limits rotation, and contributes to the overall rigidity and specific conformational properties of proteins.

Peptide Bond

A peptide bond is a covalent bond formed between the carboxyl group of one amino acid and the amino group of another, linking amino acids together to build proteins. This bond is central to the structure of proteins and determines many of their structural and functional properties.

Condensation Reaction

The formation of peptide bonds occurs through a condensation reaction, where the joining of two amino acids releases a molecule of water. This reaction is fundamentally different from hydration reactions and is key to the synthesis of peptides and proteins in biological systems.

Transcript

00:01 This question asks which of these statements concerning peptide bonds is false.

00:05 Their formation involves a reaction between an amino group and a carboxal group.

00:09 They are the primary bonds that hold amino acids together.

00:12 They have partial double bond character or their formation involves hydration reactions.

00:17 Well, if we think about peptide bond formation, we are taking one amino acid and we are linking it to another amino acid.

00:30 So right here is going to be our peptide bond.

00:36 And specifically, this will occur between the amino group of one amino acid and the carboxal group of another.

00:43 So usually it would be the amino group right here.

00:47 So this nh3 on the latter amino acid and the carboxal group on the preceding amino acid.

01:06 So if we think about the amino acids going from n terminus to c terminus, well, we have the n terminus right here, the c terminus right here, the n terminus right here, the n terminus right here, and the c terminus right here.

01:18 That is why they're called the n and c, well, because we have an n, which is the amino group and the c, which is the carboxa group.

01:24 So, yes, there will be a linking between the amino group and the carboxal group of one amino acid and another.

01:30 That's the peptide bond there.

01:32 And it will be the primary bond that holds amino acids together.

01:35 We eliminate choices a and d because we're looking for the statement that is false...

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