How might the behavior of an antigen-specific CD8+ T cell differ in the lymph node of a CCL3-deficient animal versus
a wild-type animal?
The CD8+ T cells may not be able to respond to antigen.
The CD8+ T cells may be unable to enter the lymph nodes.
The CD8+ T cells may have decreased interactions with specialized DCs licensed by CD4+ TH cells.
The CD8+ T cells may be constitutively activated, without a need for interaction with DCs.