Chem 348 Workshop 6
1. How would you carry out the following transformations? More than one step might be necessary.
OH
OH
2. Fill in the missing reagents and/or structures.
OH
1) BH3, THF
2) H2O2, OH
-
Дон
OH
Br
--
Br
MgBr
CO2
H3O
draw a mechananism
to figure out the product here.
CN HO
(see note
below)
Note: Recall from workshop 5, which referenced the hydrolysis of nitriles into carboxylic acids:
"...when treated with aqueous acid, nitriles are hydrolyzed into carboxylic acids:
CN HO
OH
R