14. S-adenosyl methionine is a compound that is being sold as supplement in the US. What is
its function as it relates to epigenetics, and what are two possible consequences of SAM
supplement consumption based on your knowledge of epigenetics? Make sure to explain your
reasoning.
15. For your senior thesis, you have investigated the enzymatic
activity of a novel H3K4 methyltransferase called MAE.
Specifically, you have been trying to find out which methylation
step MAE is responsible for, and if it uses H3K4me0, H3K4me1,
or H3K4me2 as its substrate. The results from your tests with the
three possible substrates are shown in the bar graph. You have
done every experiment five times, and the error bars on the graph
are standard errors of the mean. Explain the results of this
experiment and what it means for the activity of MAE. If you have
insufficient information to draw a conclusion, explain what
additional information or data you need to collect.