Human cells carry two versions of each gene if the gene is on an autosomal chromosome. RTK is one such gene. You compare two batches of cells:
1) Wildtype: these cells contain two functional versions for the RTK protein (normal, wildtype)
2) Mutant: these cells have one version of RTK that is fully functional, but the other version a catalytically dead RTK allele (meaning that it codes for an RTK protein that is made, put in the cell membrane, but its kinase function is non-existent)
Assume that each set of cells express the same total amount of RTK and that each is provided with the same amount of signaling molecule in the experiment.
Describe what effect you would expect to see in the mutant cells vs the wildtype cells in terms of the amount of signaling that is occurring through this pathway. Think about the mechanism of RTK function when answering this question.