2. (10 pts) The pedigree on the right tracks Duchenne
Muscular Dystrophy (DMD) in a family. Use D/d or $X^D$/$X^d$
to denote dominant/recessive or X-linked
dominant/recessive trait, respectively.
a. (2 pts) What is the most likely mode of inheritance for
DMD based on the pedigree? Why?
b. (2 pts) What are the genotypes of individuals I-1, I-2, II-2, II-3, III-1, and III-6, respectively?
c. (2 pts) If individuals I-1 and I-2 had another son, what is the chance that he would have DMD? Show
intermediate steps.
d. (2 pts) If individuals II-4 and II-5 have a fourth child, is it true that there is a 50% chance that the child
will not have DMD. Why?
e. (2 pts) If individual II-3 marries a carrier woman, what is the chance that their daughters will have
DMD?