Amino acids, pKa, and acid-base tendencies 2.1 The imidazole side chain of histidine has a pKa of 6.04. Illustrate the predominant structures for histidine at (i) pH 4, (ii) pH 8, and (iii) pH 12. (3 marks) Indicate stereochemistry at the Cα. The amino acid histidine has a side chain for which the pKa is 6.04. Calculate what fraction of the histidine side chains will carry a positive charge at pH 5.4. Be sure to show your work