Obesity is a major risk factor for the development of type 2 diabetes. What is the mechanism for this?
A. Obesity is associated with hypercholesterolemia, which impairs the circulation of insulin
B. Obesity is associated with a mutation of the miR-21 gene, which is the same gene implicated in the development of insulin resistance
C. Obesity is a result of high sugar intake, which leads to hyperglycemia
D. Obesity releases fatty acids and cytokines, which interfere with insulin receptors