Infection with the human immunodeficiency virus (HIV) causes the fatal disease called AIDS. The first drug that was effective against HIV was AZT. HIV viruses that are sensitive to AZT are not able to reproduce in the presence of AZT. When AZT was first administered to HIV-infected patients, it worked, and virus populations in the treated patients dropped dramatically. But, with time, HIV populations in the treated patients rebounded and the patients died of AIDS. These treatment failures resulted because HIV in the treated patients evolved to become resistant to AZT. You’ll need this information for the next two (2) questions.
Question 26.1 AZT 1
Q26.1 AZT 1
2 Points
Grading comment:
Upon exposure to AZT, did individual HIV viruses change over the course of their lifetime to become more resistant to AZT, so that eventually the HIV population consisted of drug-resistant forms?
Choice 1 of 2:Yes
Choice 2 of 2:No