Texts:
1. Which of the following mechanisms underlie tolerance to chronic cocaine use?
a. Reduced efficacy to inhibit DAT
b. Reduced number of dopamine D2 receptors
c. Reduced cocaine-induced dopamine release
d. Both a and b, but not c
e. a, b, and c are all correct
2. Which of the following are associated with the Negative affect/withdrawal stage of the addiction cycle?
a. Reward deficit
b. Lower hedonic set point
c. Excessive stress
d. Both a and b, but not c
e. a, b, and c are all correct