CTLA-4 and CD28 both bind B7.1. However, CTLA-4 has a higher affinity for it than CD28. Why might this be the case?
Group of answer choices
CTLA-4 is a tetramer, which results in more opportunity for binding
CD28 is a monomer, which decreases its binding efficiency
CTLA-4 engages two different B7.1 dimers at once, resulting in higher avidity
CD28 engages two different B7.1 dimers at once, resulting in higher avidity
CTLA-4 is bound to AP-2, which enhances its function