Question 50
Not yet answered
Flag question
A 49-year-old male patient presents to your clinic complaining
of fatigue, constipation, lethargy, and intolerance to cold. He is
on conservative treatment for mild hypertension "low salt diet",
he has no outstanding history of prior illness or family disease.
He is a farmer and consumes a predominantly vegetarian diet,
with water derived from a local well. On physical examination,
you notice an enlarged mass in the anterior part of his neck,
which he has noticed has been slowly growing. His vital signs
were as the following: heart rate, 60 bpm; blood pressure,
110/70 mmHg; temperature, 37.8°C. Which of the following
would you expect to be an underlying mechanism in
pathophysiology in this case?
a. Decreased hepatic thyroid-binding globulin synthesis
b. Increase follicular cell iodine concentration
c. None of them
d. Decreased thyroid peroxidase activity
e. Increased deiodinase type III activity