Which of the following best explains the metabolism of thyroxine and tri-iodothyronine during amphibian metamorphosis?
T4 (partially active form) is transformed by Type 4 deiodinase into T3 (the inactive form). Then T3 is transformed by Type 3 deiodinase into T2 (the active form), leading to metamorphosis.
T4 (the inactive form) is transformed by Type 3 deiodinase into T3 (partially active form). Then T3 is transformed by Type 2 deiodinase into T2 (the active form), leading to metamorphosis.
T4 (partially active form) is transformed by Type 2 deiodinase into T3 (the active form), leading to metamorphosis. Then T3 is transformed by Type 3 deiodinase into T2 (the inactive form).
T4 (the active form) is transformed by Type 4 deiodinase into T3 (partially active form), leading to metamorphosis. Then T3 is transformed by Type 3 deiodinase into T2 (the inactive form).