A 32-year-old man comes to the physician because of fatigue, and muscle weakness and pain since beginning pharmacotherapy 3 months ago for hypercholesteroleria. He is
active and says he experiences discomfort particularly while hiking Physical examination shows n o abnormalities. Serum studies show
Cholesterol, total
HDL-cholesterol
LDL-cholesterol
Triglycerides Creatine kinase
190 mg/dl
3 0 mg/dL.
132 mg/dL
140 mg/dL
10,000 U/L
• A) Atorvastatin
O B) Cholestyramine
• C ) Colesevelam
O D ) Garlic supplements
O E) Niacin
Which of the following substances i s t h e most likely cause of this patient's new findings?