Sickle Cell Anemia is a condition that is controlled by one gene with two alleles. Individuals who are homozygous for the affected allele have sickle-shaped blood cells that can block blood flow and cause intense pain, and these affected individuals have shorter lifespans. Heterozygotes have an advantage of being less susceptible to malaria infection because the altered hemoglobin produced by the sickle cell allele prevents the malaria parasite from completing its infection. Heterozygotes produce enough wild-type hemoglobin to avoid the negative health effects of having some mutant hemoglobin.
In one population of 100,000 people, there were the following genotypes:
SS (unaffected homozygote) = 77,440 people
Ss (unaffected heterozygote) = 21,120 people
ss (affected homozygote) = 1,440 people
a. What is the frequency of each genotype?