2. How do the IGF methylation levels of exposed individuals compare to those of the unexposed siblings?
In a typical statistical test, scientists set the level of significance at 0.05 (or 5%). This means that the groups of data
being compared need to be different enough so that the random chance that caused the experimental group to be dif-
ferent from the control group is equal to or less than 5%. By this convention, if the statistical test results indicate that
the $p$ values are equal to or less than 5%, the differences between the groups being compared are considered significant.
3. Overall, is there a significant reduction in the IGF2 methylation level in the individuals with early prenatal
exposure to famine? Explain your answer and use the $p$ value on the table to support your argument.
4. From Table 3, what is the chance that the difference in CpG 1 methylation level between the exposed individuals
and their unexposed siblings is random? Is it a high value or low value? With that, do you think the difference in
the methylation level is real or random?
5. Do the data indicate more or less IGF2 protein is produced in the famine exposed individuals?